Eucapnic vuluntary hyperpnea
Innovation for EVH provocation

Bronchial Provocation without medication.

The eucapnic voluntary hyperpnea (EVH) test is an alternative method to other indirect or direct bronchial challenge tests such as exercise challenge or methacholine challenge test1.

The huge advantage of EVH is that no medication is needed. Traditionally it has been used for elite athletes2 and is widely regarded as the gold standard for assessing exercise induced bronchoconstriction (EIB) among athletes3.

As EVH mimicries perfectly the breathing while exercising, the provocative method is the best tool to diagnose exercise-induced airway narrowing.
EucapSys is the first commercially available system which makes EVH applicable for a wide range of users. As it mixes the eucapnic gas concentration by itself, the test becomes more affordable and independent from expensive gas mixtures.

One step protocol saves time

More comfortable for the patient

Drug free provocation with dry air

Easy to implement stand-alone device

High specifity & fewer false positive results

Low operating costs

Measurement principle

1. PRE spirometry test

Before doing the provocation,
a forced spirometry sets the baseline for pre FEV1.

2. EucapSys test

Then, a dry gas mixture enriched with 5 % CO2 is hyperventilated at room temperature for about six minutes thru a breathing mask. The patient will breathe faster than normally through a mouthpiece. The maneuvre is recorded to the EUCAPSYS system box.
Measurement principle of the Eucapsys

3. POST spirometry test

After the provokational phase, the post measurements are carried out.
If the value falls below 10% of the baseline FEV1, an asthma can be diagnosed.

Benefits at a glance

1 J W Dickinson, McConell, & Whyte; Br J Sports Med; 2011; 45(14) 1126-31
2 J W Dickinson et al.; Br J Sports Med; 2006; 40:179–183
3 J H Hull et al.; Br J Sports Med; 2016; 46:1083–1093

Technical Data

Principle in situ adjustable mixture of dry air and CO2
Instant display of air flow in l/min
CO2 fraction in %
test time in min/sec
electronic PID-type
Regular CO2 fraction
Accuracy of CO2 fraction
+/- 0.1 %
Production of mixture
as needed, in accordance with consumption
Air flow rate
up to 220 l/min
CO2 supply
via a CO2 cylinder
Air flow control
using a syringe
Electrical supply
110 - 220 Volts
Electrical consumption
50 W peak
PCO2 monitoring
Thermoconductivity sensor
Control electronics
by microprocessor
approx. 15 kg
h: 55cm; l: 50cm; w: 40cm
Breathing hose
ultra-flexible, 60 cm - 180 cm long
Mouthpiece or mask
with two-way valve